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The stability and adaptability of the proposed framework are ensured through its closed-loop operation and continuous feedback mechanism

Lee HJ, Choi SC, Choi EY, et al

FDA has had the authority to require premarket authorization of all e-cigarettes and other electronic nicotine delivery systems (ENDS) since August 2016, but thus far has exercised enforcement discretion regarding the need for premarket authorization for these types of products

Leroue MK, Williamson KM, Curtin PC et al (2023) Tobacco smoke exposure, the lower airways microbiome and outcomes of ventilated children

Filters also altered the way tobacco burns, actually increasing some toxins in the smoke