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Whether this decline causes age-related healing impairment or merely correlates with it is an open question

Low-protein diets and supplementation with betaine, choline, folic acid, and vitamins B6 and B12 are standard therapies for older infants and children with CBS deficiency.12 MTHFR The MTHFR enzyme controls the conversion of inactive folate (5,10-methylenetetrahydrofolate) to active folate, 5-MTHF

doi: 10.1016/j.bbagen.2012.11.020

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