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Selected Research Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ Simon A, Monier F, Emonard H, et al

In healthy individuals, these events facilitate the recovery, which is associated with the switch from M1 to M2 anti-inflammatory phenotype of macrophages population

(2020) 180:10811097.e24

The peptide diffuses laterally through interstitial fluid before entering systemic circulation, meaning a significant fraction reaches dermal fibroblasts at concentrations 35 higher than what systemic distribution via IM would achieve

Here are the expected changes in the medications appearance and the therapeutic outcomes